NR 565 Final Exam Study Guide

The primary focus of NR 565 is advanced pharmacology, including the study of pharmacokinetics, pharmacodynamics, and the therapeutic use of medications.

Omdraaien

Pharmacokinetics is the study of how drugs are absorbed, distributed, metabolized, and excreted by the body.

Omdraaien

Pharmacodynamics is the study of how drugs affect the body, including the mechanisms of action and the relationship between drug concentration and effect.

Omdraaien

The therapeutic index is a ratio that compares the toxic dose of a drug to its therapeutic dose, indicating the safety margin of the drug.

Omdraaien

Factors influencing drug absorption include the drugs formulation, route of administration, blood flow to the absorption site, and the presence of food or other substances in the gastrointestinal tract.

Omdraaien

The first-pass effect is the metabolism of a drug in the liver that reduces the concentration of the active drug before it reaches systemic circulation.

Omdraaien

The primary routes of drug administration are oral, intravenous, intramuscular, subcutaneous, topical, and inhalation.

Omdraaien

Bioavailability is the proportion of a drug that enters the systemic circulation and is available to exert its therapeutic effect.

Omdraaien