NBME CBSE ACTUAL TEST QUESTIONS AND ANSWERS (Quiz bank with all the correct answers)

NBME CBSE ACTUAL TEST QUESTIONS AND
ANSWERS (Quiz bank with all the correct answers)
(usmle step 1) Medical examination
62 year old woman - osteoporosis - a bisphosphonate is prescribed. The expected
beneficial effect of the drug is due to which of the following? -Answer- Decreased
Osteoclast Activity
Cohot Study of elderly women - relative risk ratio for hip fractures among those who
exercise regularly is 1.2 (95% confidence interval of 1.1 to 1.8). Which of the following is
the conclusion about the effect of exercise on the risk of hip fracture? -AnswerStatistically Significant Overall Increase Risk
52 year old man goes to ER with chest pain radiating to his jaw while shoveling snow.
Pulse is 80/min and blood pressure is 130/70. The most immediate treatment
mechanism of action? -Answer- Increased nitric oxide concentration
24 year old woman - spilled hot grease on her left leg while working at a fast-food
restaurant. Exam of leg shows 7cm pink, soft, granular, edematous wound. The
formation of this tissue was most likely caused by increased activity of which? -Answera. Vascular Endothelial Growth Factor
VEGF - stimulates angiogenesiss.
TYPE III Collagen = Blood Vessels - early wound repair
27 year old man- MVC - skull x-ray shows a linear, nondepressed basal skull fracture -
increased serum osm and decreased urin osm. Following desmopressin urine osm
increases. Desmopressin's effect is due to the activation of which of the following? -
Answer- a. Adenylyl Cyclase
Adenylate Cyclase - ATP - CAMP -- PROTEKINASE A -- Ca
v2
A 10 month old boy - 4 day history of fever and cough. He attends day care center.
Chest exam shows intercostal retractions along with bilateral, diffuse wheezes and
expiratory rhonchi. The infectious agent most likely has which of the following
properties? -Answer- Mediation of Cell Entry via a fusion protein
A 17 year old girl in ED - 15 minutes after being stung by a bee. Mild light headedness
but no difficulty swallowing- Bilateral wheezing - Which is most appropriate
pharmacotherapy for this patient? -Answer- B2- Agonist
14 year old boy - 2 day history of sore throat and fever that peaks in late afternoon. 1
week of fatigue. He recentaly had sex with one partner. Physical exam show cervical
lymphadenopathy and pharyngeal erythema with a creamy exudate. DX? -AnswerInfectious Mononucleosis
57 year old man - radiation therapy for squamous cell carcinoma of the lung. Despite
therapy, tumor increases in size and he dies 6 months later. The progressive tumor
growth is due to a defect in cell cycle arrest in which of the following phases of cell
cycle? -Answer- G1
28 year old - lived in sub-Saharan Africa - until he came to the US. Temp of 100.4 -
imaging shows bilateral hydroureter and hydronephrosis. Biopsy shows marked fibrosis
and scattered granulomas. DX? -Answer- Schistosomiasis
A couple with a family history of a-thalassemia. Woman has one gene deletion and man
has two gene deletion. If the two gene is trans - what percentage of offspring will have a
two gene deletion? -Answer- 50