APEA 3P CCK PRACTICE EXAM 2024 NEW UPDATE QUESTIONS AND ANSWERS

APEA 3P CCK PRACTICE EXAM 2024
NEW UPDATE QUESTIONS AND
ANSWERS
What effects do CCK and gastrin share (or not share) at physiologic
concentration?
CCK and gastrin do not share any effects at normal physiologic concentration.
While CCK and gastrin do not share any effects at normal physiologic
concentration, how do they compare at pharmacologic doses?
They have identical actions on GI function when pharmacologic doses are administered.
What is the role of gastrin?
Stimulates gastric acid secretion and mucosal growth throughout the stomach and
intestines under physiologic conditions.
What is the role of CCK?
Stimulates growth of the exocrine pancreas and inhibits gastric emptying under normal
conditions.
Stimulates gallbladder contraction, relaxation of the sphincter of Oddi, and secretion of
bicarbonate and enzymes from the exocrine pancreas.
Patient has NSAID-associated gastritis or peptic ulceration. Pentagastrin
administered intravenously would lead to a lower than expected (less than
normal) increase what?
Gastric acid secretion
When inflammation affects the gastric corpus, parietal cells are inhibited, leading to
reduced acid secretion.
(Pentagastrin is a synthetic gastrin composed of the terminal four amino acids of natural
gastrin plus the amino acid alanine, but it has the same physiologic properties of natural
gastrin.)
What can virtually eliminate the secretion of acid during the gastric phase?
Proton pump inhibitor (omeprazole)
Inhibits all acid secretion by DIRECTLY inhibting the H+/K+ ATPase.
(Bypass individually blocking gastrin, acetylcholine, and histamine)
Patient with peptic ulcer was given omeprazole. As time progressed after
administration, what was most likely to increase?
Gastrin secretion
(by G cells is increased by increased luminal pH as part of a negative feedback loop)
Increased luminal pH decreases histamine, secretin, and SST secretion
What is the direct physiologic effect of the various hormones on gastric acid
secretion?
Stimulates: Gastrin
Inhibits: Secretin, GIP
No effect: CCK, Motilin
Newborn does not pass meconium in the first 24 hours. Has distended abdomen
and begins vomiting. What is most likely the obstructed portion of his gut?
Sigmoid colon
This is Hirschsprung disease. It is characterized by a congenital absence of ganglion
cells in the distal colon.
Man eats a healthy meal. 35 minutes later, the ileocecal sphincter relaxes and
chyme moves into the cecum. Gastric distention leads to relaxation of the
ileocecal sphincter by the way of which of the following reflexes?
Gastroileal reflex
First part of reflex name (gastro-): origin of reflex
Second part (-ileal): target of refle