Question
In addition to life saving interventions, what prescription medication will
most benefit this patient at thistime?
Answer Choices
1 Furosemide (loop
diuretic) 2
Prednisone
(glucocorticoid)
3 Tranexamic acid
(antifibrinolytic agent)4
Labetolol (beta blocker)
5 Nimodipine (calcium
channel blocker)ANS: 5
Nimodipine (CCB)
Nimodipine, a calcium channel blocker, has been shown to improve outcomes
in patients following aneurysmal SAH. The mechanism of action is thought to
be prevention of ischemia. Glucocorticoids (e.g.,prednisone) are often utilized
in patients with SAH because they offer symptomatic relief of headache and
neck pain, but they have not been proved to decrease cerebral edema.
Antifibrinolytic agents (e.g., Tranexamic acid) can be utilized in patients with a
diagnosed aneurysm who cannot undergo directed treatment, but they are not
routinely used following aneurysmal rupture. Labetalol (a beta blocker) may
be utilized to treat elevated BP, but it must be used with caution because it can
also decrease cerebral perfusion. Diuretics (e.g., furosemide) have no
identified role in the treatment of aneurysmal SAH.
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