Leg mij uitgebreid het volgende onderwerp uit: Background: Nutritional status is paramount in Cystic Fibrosis (CF) and is directly correlated with
morbidity and mortality. The first ESPEN-ESPGHAN-ECFS guidelines on nutrition care for infants, chil-
dren, and adults with CF were published in 2016. An update to these guidelines is presented.
Methods: The study was developed by an international multidisciplinary working group in accordance
with officially accepted standards. Literature since 2016 was reviewed, PICO questions were discussed
and the GRADE system was utilized. Statements were discussed and submitted for on-line voting by the
Working Group and by all ESPEN members.
Results: The Working Group updated the nutritional guidelines including assessment and management
at all ages. Supplementation of vitamins and pancreatic enzymes remains largely the same. There are
expanded chapters on pregnancy, CF-related liver disease, and CF-related diabetes, bone disease,
nutritional and mineral supplements, and probiotics. There are new chapters on nutrition with highly
effective modulator therapies and nutrition after organ transplantation. De uitleg moet geschreven zijn op het niveau van de Universiteit.
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