WGU D115 Master set advanced Pathophysiology for the advanced practice Nurse 2023 graded A+

Which type of genetic disease affects males more frequently than females? - Correct
Answer-Sex-Linked recessive. Since males only have one X and one Y, if the affected
chromosome has the illness, it will be expressed.
In which two conditions are chromosomal abnormalities the leading known cause? -
Correct Answer-Intellectual disability and fetal miscarriage. Chromosome abnormalities
are the leading known cause of intellectual disability and fetal miscarriage.
What are three examples of prenatal diagnostic studies? - Correct Answer-Chorionic
villus sampling (CVS), amniocentesis, and preimplantation genetic testing (PGT) are
examples of prenatal diagnostic studies and are performed in vitro. CVS is a form of
genetic testing that provides genetic information found in utero and is usually performed
between weeks 11 and 14 of pregnancy. An amniocentesis is a form of genetic testing
that evaluates amniotic fluid and is usually performed during the second trimester,
between weeks 15 and 20 of pregnancy. PGT is performed on the embryo prior to
implantation.
Which genetic disorder is characterized by the presence of a zygote having one
chromosome with a normal complement of genes and one chromosome with a missing
gene? - Correct Answer-Cri du chat syndrome (translated as "cry of the cat") is caused
by a DNA deletion. This term describes the cry often heard from a baby affected by the
syndrome. Cri du chat syndrome can present as a microcephalic, low birth-weight baby
with a piercing cry.
How can an X-linked recessive disease skip generations? - Correct Answer-The
disease can be transmitted through female carriers.
Since females have two copies of the X chromosome, the mother may provide an
unaffected X to a daughter or son. Furthermore, a daughter may not show signs of the
disease because she has the other X (the only X the father can give to a female) to
cancel it out